$ sudo apt install python3-pip
$ pip3 install biopython
$ python3
Python 3.7.3 (default, Oct  7 2019, 12:56:13) 
[GCC 8.3.0] on linux
Type "help", "copyright", "credits" or "license" for more information.
> import Bio
> print(Bio.__version__)
1.74
> from Bio.Seq import Seq
> my_seq = Seq("AGTACACTGGT")
> my_seq
Seq('AGTACACTGGT')
> my_seq.complement()
Seq('TCATGTGACCA')
> my_seq.reverse_complement()
Seq('ACCAGTGTACT')